Expanding and accelerating biomedicinal chemistry with high confidence computation and state-of-the-art experiments


In March 2022, the Czodrowski lab moved to the Department of Chemistry at JGU Mainz.
The Czodrowski lab investigates the proton transfer in pharmaceutical relevant drug candidates. Here, a special focus is placed on thermodynamics and kinetics, so that principles and possible rules for the design of improved drug candidates can be drawn from this. In addition to experimental methods, modern approaches from artificial intelligence and data science are also used.

Methods


  • Isothermal titration calorimetry¬†
  • pKa measurement by UV/Vis and potentiometry
  • Protein expression and purification
  • Molecular biology and protein crystallography
  • Python programming
  • Machine Learning
  • Tools development

Job vacancy


If you are interested in doing a bachelor thesis, master thesis or an internship in our group, please contact us via the contact form or write an email to:

Available positions:
PhD position
Thesis topics for master students or bachelor students

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Cooperation partners


Advanced Machine Learning or innovative drug discovery