Expanding and accelerating biomedicinal chemistry with high confidence computation and state-of-the-art experiments
In March 2022, the Czodrowski lab moved to the Department of Chemistry at JGU Mainz. The Czodrowski lab investigates the proton transfer in pharmaceutical relevant drug candidates. Here, a special focus is placed on thermodynamics and kinetics, so that principles and possible rules for the design of improved drug candidates can be drawn from this. In addition to experimental methods, modern approaches from artificial intelligence and data science are also used.
Isothermal titration calorimetry
pKa measurement by UV/Vis and potentiometry
Protein expression and purification
Molecular biology and protein crystallography
If you are interested in doing a bachelor thesis, master thesis or an internship in our group, please contact us via the contact form or write an email to: